INTERACTIVE CLINICAL CASE – Advances in early diagnosis of congenital hypopituitarism


Disorders of glucose metabolism are frequently observed in newborns and children with chronic diseases. The challenge for clinicians is in judging when they are transient and self-limiting, when they are iatrogenic to other treatments, or when they underlie a chronic disorder of glucose homeostasis.  The clinical scenario should be carefully considered over time, as growth disorders can be suspected largely in advance of growth failure, with metabolic alterations sometimes one of the presenting signs. In particular, a patient’s phenotype can be a key feature in working out a potential diagnosis affecting growth and glucose metabolism. Specific signs may promptly lead to tailored investigations, early diagnosis and, therefore, to well-timed treatment. The physician’s ability to recognize crucial signs can change patients’ medical history and largely improve their quality of life. Professor Marco Cappa, an experienced leader in the field of complex growth disorders, will guide participants of this activity through an intriguing real clinical case, explaining how some dysmorphisms might accelerate the diagnostic path in specific congenital growth disorders.


By attending this online interactive activity, learners will:

  1. Explore how the clinical phenotype should be considered in children with disorders of glucose metabolism
  2. Learn how to use the clinical phenotype to improve/shorten the diagnostic path for growth disorders
  3. Discuss which are the more common challenges in the making-decision process in children with glucose and growth disorders.


This program is intended for all healthcare providers involved in the care of diseases affecting glucose metabolism and growth in childhood. The content will be particularly relevant to specialist care providers, including pediatric endocrinologists, diabetologists, pediatricians and pediatric metabolic specialists. However, any healthcare professionals involved in managing children with chronic conditions affecting growth and their quality of life will find this online event advantageous for his/her professional development.


Marco Cappa
Director of Endocrinology Unit
Department of Pediatrics
Bambino Gesù Children’s Hospital
Rome and Palidoro, Italy


Marco Cappa is Chief of the Endocrinology Unit of the Department of Pediatrics, Bambino Gesu Children’s Hospital, Rome and Palidoro, Professor of Pediatric Endocrinology and Pediatrics at the University La Sapienza, Rome and Professor of Pediatrics at the University Tor Vergata, Rome, Italy. He is also part of the national anti-doping organization (CEFT) Nado Italia COMI (national site of the World Anti-Doping Agency [WADA]). Professor Cappa’s specialties include endocrinology, pediatrics and sports medicine. His main scientific areas of interest include neuroendocrinology, genetics, growth hormone testing, adrenoleukodystrophy, congenital adrenal hyperplasia and Prader-Willi syndrome. He is a member of several organisations, including the Italian Pediatric Endocrinology and Diabetes Society, the European Society of Neuroendocrinology, The Endocrine Society, and the European Society for Pediatric Endocrinology. He serves on the editorial board of the Journal of Sports Medicine and Physical Fitness and the Italian Journal of Pediatrics, and he is a reviewer for the Journal of Clinical Endocrinology and Metabolism, the Journal of Endocrinology Investigation, the Italian Journal of Pediatrics, the Journal of Clinical Endocrinology and Metabolism, Clinical Endocrinology, the Journal of Neurology, Neurosurgery and Psychiatry and the Journal of Pediatrics.

Professor Cappa is a widely published author, with an H-index of 39, and more than 400 publications in a wide variety of top tier journals.


Scientific Seminars International Foundation adheres to guidelines of the European Accreditation Council for Continuing Medical Education (EACCME®) and all other professional organizations, as applicable, which state that programs awarding continuing education credits must be balanced, independent, objective and scientifically rigorous. Investigative and other uses for pharmaceutical agents, medical devices and other products (other than those uses indicated in approved product labelling/package insert for the product) may be presented in the program (which may reflect clinical experience, the professional literature or other clinical sources known to the presenter). We ask all presenters to provide participants with information about relationships with pharmaceutical or medical equipment companies that may have relevance to their lectures. This policy is not intended to exclude faculty who have relationships with such companies; it is only intended to inform participants of any potential conflicts so that participants may form their own judgements, based on full disclosure of the facts. Further, all opinions and recommendations presented during the program and all program-related materials neither imply an endorsement nor a recommendation on the part of Scientific Seminars International Foundation. All presentations represent solely the independent views of the presenters/authors.

The faculty provided information regarding significant commercial relationships and/or discussions of investigational or non-EMEA/FDA approved (off-label) uses of drugs:

Marco Cappa                         Declared receipt of grants and contracts from Merck-Serono, Novo Nordisk and AMRYT and receipt of honoraria or consultation fees from Sandoz and Novo Nordisk.

All Scientific Seminars International Foundation programs are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products. These views are the responsibility of the named speakers, and do not represent an endorsement or recommendation on the part of Scientific Seminars International Foundation.


This activity will be in English.

15 December 2021


Scientific Seminars International Foundation
Senior CME Manager: Flaminia Masprone
T +39 380 1504116 – F +39 06 4827169

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This independent educational program is made possible thanks to an educational grant received from Merck Healthcare KGaA Darmstadt Germany.

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